For reference, Rebirth . Each laser is emitted for about one second and hits twice, so it is possible to destroy some two-stage enemies in one shot (Globins and Hives along with the flies they spawn on death), or to strafe the shot over multiple enemies. Any subsequent hits give +0.4 Tears Up and will ignore the normal fire rate cap, Greatly decreases damage (x0.33 damage multiplier), Individual tears gain random worm effects (e.g. Using it with less than 5 coins does nothing, UNLOCK: Unlock this item by collecting 99 coins then spending all of them in the same run, Item Pool: Item Room, Greed Mode Item Room, Upon use, grants use of Brimstone for the current room, If used twice in the same room, the brimstone laser becomes massive and deals +1.8 more damage, Using it more than twice in the same room will give a damage increase each time. Trinkets You can use Lord of the Pit to get yourself out of sticky situations, when you lose a roll and are going to take damage, you can use this item to avoid that damage, you can choose to keep attacking that monster, or fight a weaker one. 5c pickups become 3c. Item Icon Kills poop bosses when used - Dingle, Dangle and Brownie, * item room, treasure room, item room pool, silver spoon handle, grey, gray, white, toilet. Cannot be obtained and has no use for any other character, Birthright is a Shop item that has unique effects depending on what character you're playing as, This is the item Tainted Blue Baby (???) 5 keys = 100% chance. blood clot es un aumento de dao parcial debido a que no solo una de dos lagrimas disparadas tengan mas dao este item es de la pool de habitacion del tesoro , bosses o por el item de polyp este item se aprobecha mas con el item de 20.20 ya que en este caso las probabilidades de que mas de una sola lagrima tenga ese aumento de dao Isaac- Issac gets Tech X, Spoon bender, some damage up, the cancer trinket, and the boss warp card. Update 1.7.7 has arrived for The Binding of Isaac: Rebirth, and here's the full list of changes and fixes added with this patch. Larry Jr.) it will split them into 2 smaller enemies with half the number of sections they used to have, If the enemy normally has a mechanic that splits it (e.g. Symptoms of a blood clot include: throbbing or cramping pain, swelling, redness and warmth in a leg or arm. This means you need a way to teleport out of the Mom's Foot boss fight. * e coli, item room, treasure room, item room pool, tampon, bloody, red, white, red sperm, ecoli, Isaac's tears turn into large scythes that pierce through enemies (Similar to how Death's scythes look), UNLOCK: Unlock this item by beating Challenge #17 (Waka Waka), * devil pool, devil room pool, devil deal, item room, treasure room, item room pool, axe, silver, Manage all your favorite fandoms in one place! ( : Guppy's Tail Mom's Purse Bob's Curse Pageant Boy Scapular Infestation The Mulligan Habit Spirit Of The Night Ankh Celtic Cross Mitre Fate The Black Bean Holy Grail Dead Dove Pyro 3 Dollar Bill Mom's Coin Purse Box), ( : Guppy's Paw IV Bag Best Friend Remote Detonator Guppy's Head Prayer Card Notched Axe Crystal Ball Crack The Sky The Candle D20 Spider Butt Dad's Key Portable Slot White Pony Blood Rights), Books: The Bible The Book of Belial The Necronomicon Book Of Revelations Book of Shadows Anarchist Cookbook The Book Of Sin Monster Manuel UNLOCK: Unlock this item by defeating Mother in the Corpse II as Lilith, Item Pool: Item Room, Red Chest, Curse Room, During the transition between floors, this item shows you a preview of the item that will spawn in the item room, and the boss that will appear, This effect will work even if you have Curse of the Blind, but the item will still appear as a ? *, stone, rock, grey, gray, white, dice, pip, broken, die, While held this trinket causes all pickups and enemies to move slowly towards you, Will also attract the Mom's Foot and Ultra Greed door entities, *, white, grey, gray, pill, medicine, drug, Randomly Isaac will gain a camouflage for a few seconds and all enemies in the current room will have a confused status effect applied to them, This trinket can be used to open the door to Mausoleum in Depths II, Gives a small chance to spawn a friendly attack spider while in a hostile room with enemies, Leaves a pool of green creep under all bombs you place, which damages enemies that walk over it, *, green, bogey, snot, ocarina, bobs bladder, bob bladder, Gives a +6.66% chance of a getting a small battery after clearing a room, Gives a +2.0% chance for pickups to be small batteries, Gives a +5.0% chance to add an extra charge to your active item after clearing a room, *, metal, grey, gray, silver, pill, cross, Exploding bombs now have a chance to drop another bomb that you can pick up, Higher chance to find crawl spaces when exploding rocks, UNLOCK: Unlock this trinket by beating Challenge #27 (Brains), *, toe, finger, thumb, grey, gray, black, red, yellow, Gives a different trinket effect per room, randomly choosing between any of the other available trinkets in the game. These stack with multiple secret rooms - The first one gives +1.00 Tears Up, then all future ones give +0.5. After a few seconds, he will quickly attack each target, chaining higher damage for each enemy it hits, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Judas, When used this will cause 8 poison farts that leave a brown creep behind, and then drop 7 Butt Bombs very quickly, Standing in the creep gives you +1 Damage Up and +1.35 Tears Up, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Blue Baby, For the current room, 14 Dead Birds fly in from off the screen and attack all enemies, dealing low but frequent damage, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Eve, Isaac gains the Berserk! However, If you also have flying you will always take damage, * astrology, astronomy, item room, treasure room, item room pool, blue, glow, circle, bomb, A random chance when you take damage to get an invincibility shield for 7 seconds, The chance to get an invincibility shield is affected by your luck stat and at +10 Luck it will activate every time you get hit, Converts all negative pills into their positive counterparts e.g. cash money, When used, Isaac gains homing shots and +3.0 Range Up for the current room, Counts as 1 of 3 book items needed towards the Bookworm transormation, * library pool, library room, book room pool, item room, treasure room, item room pool, The signals tell your spleen to release . He was born May 5, 1976, in Bangor, Maine, to James and Sarah Blood. It is possible to charge before entering a room so that the first shot can be fired immediately. However after the first damage tick, there is an additional . It isn't 100% effective but the effect is very strong and will deflect most shots under a bullet hell situation. . Last time I was playing greed mode with Lilith I came upon Blood Clot pickup which normally causes a character to shoot one normal tear and one damage-enhanced alternately. Manage all your favorite fandoms in one place! UNLOCK: Unlock this item by defeating Ultra Greed as Apollyon, At the start of each new hostile room, you have a 20% chance to gain a random charmed familiar which will fight for you, The charmed enemy has its own health bar and will die if it takes enough damage, Charmed enemies persist between each room and floor for as long as they stay alive, Allows you to have more than one charmed familiar at a time if you can keep them alive, * pokemon, phone, black, green, blue, gps, Every time one of your tears hits an enemy, it has a chance to start bleeding, which will cause it to take damage every 5 seconds, The bleed damage dealt by BackStabber is based on how quickly an enemy is moving (faster enemies take more damage), Damaging enemies from behind gives the bleed effect a 100% chance to apply, While an enemy bleeds, they leave behind creep that damages other enemies, The tear that inflicts the bleed effect also deals double damage, *, knife, dagger, red, heart, silver, knife, When used, Sharp Straw will deal damage to all enemies in the room, The damage dealt is equal to Isaac's current tear damage plus 10% of the enemy's max health, Every time this item deals damage, it has a 15% chance to drop 1/2 red hearts, REPENTANCE - Sharp Straw is now only able to generate half red hearts (previously, it generated half soul hearts if the player had no heart containers), A razor blade orbital that deals contact damage and applies the bleeding status effect to enemies and bosses, which will cause them to take damage every 5 seconds, The contact damage dealt by Mom's Razor is based on how quickly an enemy is moving (faster enemies take more damage), Its speed is not affected by the Guardian Angel item, An eye orbital that shoots tears that deal 3.5 damage and deals 2 contact damage per tick to enemies, The damage dealt by this orbital does not scale with damage upgrades, REPENTANCE - Bloodshot Eye now blocks enemy shots, has increased shot speed and rate of fire, and now only shoots when lined up with enemies, When used, spawns a charmed random white delirium version of a boss, that will fight for you and kill other enemies for the rest of the current room, Possible bosses spawned include most bosses in the game, Some bosses' effects can harm Isaac. Items: Inner Eye, Almond Milk, Brimstone, Pentagram, Brain Worm. First, chemical signals cause the injured vessels to narrow to prevent more blood from leaking out. 8 coins = Slot Machine, While playing as Tainted Cain you get a visual interface to see what items are in the bag, allowing you to see what item will be created and swap out specific consumables, Has other uses - Will deal 3 damage to enemies it hits, and can be used to quickly push bombs and objects across rooms, Tainted Cain starts with this item, but can be used by any character after unlocking it and finding it in the item room, Cannot be used to craft another Bag of Crafting, UNLOCK: Unlock this item by defeating Delirium as Tainted Cain, While holding flip, a ghost item will appear behind item pedestals upon entering Item Rooms and Shop that cannot be interacted with, When activated, all real items in the room will be swapped with the ghost items behind them, The ghost item stays there even if you take the regular item, allowing you to use Flip to get both of them, Does nothing with item pedestals that don't have a ghost item behind them, When playing as Tainted Lazarus, activating Flip also changes you between Lazarus and Dead Lazarus, Tainted Lazarus starts with this item, but can be used by any character after unlocking it and finding it in the item room, UNLOCK: Unlock this item by defeating Delirium as Tainted Lazarus, When used, gives you an orbital flame which represents another random passive item in the game. These damage increases do not stack with each other. You still take damage however when using Blood Donation machines and Devil Beggars, *, spikes, spikey, spike rock, greyhost, grey host, Causes all pedestal items to show up as rotating items, that swap every 1 second between the original spawned item and a HP up item. Spawns coins as The Keeper, I can see forever - Opens secret room and super secret room entrances on the current floor, I found pills - Changes the appearance of Isaac's face for the current room (Cosmetic change only), Lemon Party - Spawns a large yellow pool on the floor around you, damaging enemies which walk in it, Paralysis - Prevents you from moving for a short while, Pheromones - Applies the charm effect to all enemies in the room for a short while, Puberty - Causes Isaac to grow hair for the rest of the run. Old now. Haemolacria is an unlockable passive item added in The Binding of Isaac: Afterbirth (Booster Pack #4). - Every HP upgrade is now worth 2 soul hearts. 's unique poops, Corn poop - Spawns a blue fly every 2 seconds, Flaming poop - Leaves behind fire that damages enemies, Black poop - Creates slowing black creep. Effects grey, gray, blue, moms eyeshadow, Tears now have a chance to concuss enemies, causing them to walk around dazed and confused for a short period of time, The chance to concuss enemies is affected by your luck stat and at +27 Luck it will activate every time, * item room, treasure room, item room pool, grey, gray, silver, ingot. Mom's Knife: . * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, Releasing Dark Esau will cause him to charge directly at Jacob and deal damage to anything in his path. One of the sounds lasers can make when synergizing with Monstro's Lung. The creep deals 2 damage per tick while enemies stand in it, Lazarus' revived form (Lazarus II) respawns with this item, * item room, treasure room, item room pool, blood drop, red blood, drip, Gives Isaac a guaranteed devil or angel room on every floor that they can appear, even if you have already beaten the boss and it didn't show up originally, Taking the Goat Head (or any other item) in a Devil Deal bars you from encountering Angel Rooms naturally. If the player has all mapping effects, it grants the "I can see forever!" Items The Lost starts with this item after donating 879 coins to the Greed Donation Machine. It will also sometimes randomly drop bombs. The floor generation can fail and cause the guaranteed Planetarium to not spawn sometimes. Seeds Well Cain is supposed to be lucky right? In Afterbirth+, taking 3 of this pill gives the Adult transformation, Pretty Fly - Gives Isaac +1 fly orbital, which blocks enemy projectiles and damages fly-type enemies on touch, Range Down - Reduces your range stat by -2, Range Up - Increases your range stat by +2.5, R U a wizard? the lost item pool, A familiar that follows Isaac and fires black tar tears, which slow enemy movement and projectile speed for a few seconds, Little Gish fires tears at a rate of 1 tear per second, A Guaranteed drop from the Gish boss fight, UNLOCK: Unlock this item by beating the Depths 20 times and killing the Gish boss, * item room, treasure room, item room pool, grey, gray, yellow, eyes, face, A familiar that follows Isaac and fires homing tears that deal 3.5 damage each, Has a high chance to drop from the Steven boss fight, Little Steven fires tears at a rate of 1 tear per second with a slightly longer range than other familiars, UNLOCK: Unlock this item by killing the Steven boss for the first time, * boss room pool, boss room item, item room, treasure room, item room pool, black, baby, white, eyes, UNLOCK: Unlock this item by killing Mom (Mom's Foot or Mom's Heart) using The Bible, * angel room pool, god room pool, angel room item, boss room pool, boss room item, item room, , Almond Milk, Brimstone, Pentagram, Brain Worm deflect most shots under a bullet situation... 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