Assets under management grew from $250 million in 2003, to $15.2 billion as of November 15th, 2022. (f)Purchase There was a marginal increase last quarter. enable the Investor to propose a replacement Investor Designee in accordance with the terms of this Agreement. Terms of Submission IN WITNESS WHEREOF, each of the parties hereto has executed this Amended and Restated Keep reading this article to learn more about Baker Brothers Advisors. Its flagship products include JAKAFI, which is a drug for the treatment of myelofibrosis and polycythemia, and Iclusig, a kinase inhibitor to treat chronic myeloid leukemia. To ensure our website performs well for all users, the SEC monitors the frequency of requests for SEC.gov content to ensure automated searches do not impact the ability of others to access SEC.gov content. See how we calculate 13F filing performance here, Baker Brothers Portfolio & 4 Largest Public-Equity Investments, 20 Highest Yielding Monthly Dividend Stocks. Form D contains basic information about the offering and the company. Note that this policy may change as the SEC manages SEC.gov to ensure that the website performs efficiently and remains available to all users. Baker Brothers Life Sciences, L.P. is one of the larger private funds with 13.9 billion in assets. 12b-2 under the Securities Exchange Act of 1934, as amended. How do I update this listing? or to simply have an email sent to you whenever we receive a new ACADIA Pharmaceuticals focuses on the development and commercialization of small molecule drugs aimed at unmet medical needs in central nervous system disorders. Revenues have expanded from around $169 million in 2010 to $3.33 billion over the past four quarters. Si vous y consentez, nous et nos partenaires utiliserons galement des cookies et autres traceurs de mesure daudience, de publicit et de rseaux sociaux, dont le dtail des finalits est accessible depuis le bouton Grer les paramtres . Analytical cookies are used to understand how visitors interact with the website. The stock is trading at a forward P/E ratio of ~28, which is a near-record low valuation multiple for the company. In March of 2021, Acadia had announced deficiencies identified by the FDA regarding its marketing application for Pimavanserin in hallucinations and delusions associated with dementia-related psychosis. These cookies help provide information on metrics the number of visitors, bounce rate, traffic source, etc. The largest five stakes are Seagen, BeiGene, Incyte, Kodiak Sciences, and Ascendis Pharma A/S. The stock currently trades at $47.55. Note: 13F filing performance is different than fund performance. BAKER BROTHERS LIFE SCIENCES, L.P. By: BAKER BROS. ADVISORS LP, management company and investment adviser to Baker Brothers Life Sciences, L.P., pursuant to authority granted to it by Baker Brothers Life Sciences Capital, L.P., general partner to Baker Brothers Life Sciences, L.P., and not as the general partner. Baker Bros Advisors was founded in 2000 and is based in New York City. For more information, contact opendata@sec.gov. Performance & security by Cloudflare. Additionally, Baker Bros. dont intend to dilute their status as highly successful biotech investors, as they do not intend to ever allocate assets in other industries. According to Crain's Chicago Business, some of Chicago's fledgling biotech companies such as Xeris Pharmaceuticals and Evanston-based Aptinyx went public in 2018 alongside other local life sciences startups an indication of investors' mounting interest in the city's biotech scene. (e)IPO means the Companys first underwritten public The largest five stakes are Seagen, BeiGene, Incyte, Kodiak Sciences, and Ascendis Pharma A/S. closing of the IPO and for three (3)years thereafter, at any time at which the Investor and its Affiliates, collectively, beneficially own (i)the Required Shares and (ii)at least 2% of the Companys then-outstanding voting Please disable your ad-blocker and refresh. Notices shall be delivered as follows: Wilmer Cutler Pickering Hale and Dorr LLP, Gunderson Dettmer Stough Villeneuve Franklin& Hachigian, LLP. Performance over the past three years has lagged, but it could be a temporary phase for the fund, which, after all, focuses on long-term returns. each case, must be in writing and shall be effective only to the extent specifically set forth in such writing. We also use third-party cookies that help us analyze and understand how you use this website. Investors following the companys 13F filings over the last 3 years (from mid-November 2019 through mid-November 2022) would have generated annualized total returns of -0.82%. SEC form, multiple filers or classes of filers, and much more.***. THIS AMENDED AND RESTATED NOMINATING AGREEMENT (this Agreement), dated as of April22, 2021, by and among TScan The current minimum investment for Baker Brothers Life Sciences, L.P. is $40000000. 14159 capital, l.p., relying adviser, bbi (baker brothers investments), baker/tisch capital, l.p., relying adviser, baker brothers life sciences capital, l.p . In this respect, the Company shall give the Observer copies of all notices, minutes, consents, and other materials that it provides to its directors at validity, legality and enforceability of the remaining provisions shall not in any way be affected or impaired thereby. Click to reveal Is this happening to you frequently? designate an individual as a nominee to the Board of Directors or its rights under this Agreement. Management owns 12 percent of the fund. The funds philosophy stands in holding its investments ordinarily for three years, though its higher-conviction investments can be seen held for longer. Baker Bros held its position steady last quarter, though the fund still owns nearly 11.4% of the company. benefit of, and be binding upon, the successors, assigns, heirs, executors, and administrators of the parties hereto. To allow for equitable access to all users, SEC reserves the right to limit requests originating from undeclared automated tools. 33. Form D is a form to be used to file a notice of an exempt offering of securities with the Securities and Exchange Commission. Michael Goller has served as a member of the Board of Directors since 2015. The Baker Brothers Entities nominated Fuchs as one of eight nominees to the board of directors at AnorMED, Inc. and, it can be inferred, given the timing, that Fuchs was also appointed by the Baker Brothers Entities to the Mirati If any provision of this Agreement shall be invalid, illegal or unenforceable, the WHEREAS, the Company and the Investor are parties to that certain Nominating Agreement dated January15, 2021 (the Original value remained steady this quarter at $22.77B. I am not receiving compensation for it (other than from Seeking Alpha). These shares were traded by Baker Brothers Life Sciences, L.P. ("Life Sciences", and together with 667, the "Funds") in multiple transactions at prices ranging from $84.23 to $84.88, inclusive. Its clinical stage products include ruxolitinib, a steroid-refractory chronic graft-versus-host-diseases (GVHD) It also develops Retifanlimab that is in Phase II clinical trials for MSI-high endometrial cancer, merkel cell carcinoma, and anal cancer. I have no business relationship with any company whose stock is mentioned in this article. of the Election Meeting and the term of such Investor Designee as a director on the Board of Directors does not expire at such Election Meeting. Last significant activity was in Q4 2019 which saw a ~20% stake increase at prices between ~$14.50 and ~$76. Common Stock, the Company shallsupport the nomination of, and cause the Board of Directors (or the nominating committee thereof), subject to the requirements of fiduciary duties under applicable law, to include in the slate of nominees But opting out of some of these cookies may have an effect on your browsing experience. Additionally, 100% of the funds holdings comprise companies operating in the healthcare sector. This SEC practice is designed to limit excessive automated searches on SEC.gov and is not intended or expected to impact individuals browsing the SEC.gov website. [SIGNATURE PAGE TO TSCAN THERAPEUTICS AMENDED The stock currently trades at $3.46. Major activity in the last decade follows. exercise any right, power or remedy accruing to the Investor hereto upon any breach or default of the Company under this Agreement, shall impair any such right, power or remedy of the Investor nor shall it be construed to be a waiver of any such Since then the activity has been minor. We reserve the right to block IP addresses that submit excessive requests. Since then, the activity has been minor. President, Rosenberg Ach Foundation. By using this site, you are agreeing to security monitoring and auditing. If you accept, we, along with our partners, will also use analytics, advertising and social media cookies and other trackers, whose the details of the purposes are accessible from the button Set Preferences. PitchBook helps you see a funds investments based on target industry, year and deal typeso you can quickly understand its strategy at a glance. I wrote this article myself, and it expresses my own opinions. This quarter saw a marginal increase. It is the funds second-largest holding, occupying 14.9% of its total portfolio. The stock currently trades at $13.72. This cookie is set by GDPR Cookie Consent plugin. The current minimum investment for Baker Brothers Life Sciences, L.P. is $40000000. Shares started trading at ~$49 and currently goes for $13.27. The cookie is used to store the user consent for the cookies in the category "Performance". Baker Brothers Life Sciences LP; Firm: Fund # CIK # 0001363364: Sale: Fund: Phone: 2123395633: Address: 667 Madison Avenue New York, New York 10065: Source Disclosure: I/we have a beneficial long position in the shares of ACAD, BMRN, INCY either through stock ownership, options, or other derivatives. This cookie is set by GDPR Cookie Consent plugin. The fund is located in New York, New York and will invest in United States. Baker Brothers stake goes back to funding rounds prior to the IPO. executed questionnaire in the form that the Company provides to its outside directors generally. This information is available in the PitchBook Platform. I/we have a beneficial long position in the shares of ACAD, BMRN, INCY either through stock ownership, options, or other derivatives. as adjusted for any stock split, stock dividend, combination, or other recapitalization or reclassification or similar transaction). understanding and agreement between the parties with regard to the subject matter hereof and supersedes all prior oral or written (and all contemporaneous oral) agreements or understandings with respect to the subject matter hereof. Note:Do to a changed CUSIP number, Baker Brothers holding Evofem Biosiences (EVFM) is not in the spreadsheet. These cookies will be stored in your browser only with your consent. Despite a losing win-record, the firm has managed to post outstanding returns through prudent position sizing. All remedies, either under this Agreement, or by law or otherwise afforded to any party, shall be cumulative and not alternative. The bottom line has never been positive, however, with losses persisting even as sales are growing. The stock is now well below that range at $9.78. Get the full list, Morningstar Institutional Equity Research. This cookie is set by GDPR Cookie Consent plugin. We'll assume you're ok with this, but you can opt-out if you wish. (c)Bylaws means the Bylaws of the Company, as may be amended, restated or otherwise modified Baker Brothers 13F portfolio value remained almost steady at $22.77B this quarter. laws of the State of Delaware, without giving effect to its principles of conflicts of laws. (h)Series C Preferred means shares of the Companys Series C Preferred Stock, par value (g)Required Shares means at least 75% of the shares of the Series C Preferred purchased by NEW YORK, NY Note: We do not offer technical support for developing or debugging scripted downloading processes. Baker Brothers Life Sciences is a 2006 vintage buyout fund managed by Baker Brothers Investments. Notices must be given: (a)by personal delivery, with receipt acknowledged; (b)by email followed by hard copy delivered by the methods Contact Information Fund Manager Baker Brothers Investments Fund Category Shares started trading at ~$18 and currently goes for $27.21. Note: Baker Brothers controls ~26% of the business. There was a marginal increase this quarter. argenx SE (ARGX): The ARGX stake was primarily built in Q4 2017 at prices between ~$22.50 and ~$63. I am not receiving compensation for it (other than from Seeking Alpha). from time to time. The stock currently trades at ~$142. Functional cookies help to perform certain functionalities like sharing the content of the website on social media platforms, collect feedbacks, and other third-party features. Note: Regulatory filings since the quarter ended show them owning ~33.8M shares of Incyte. under clause (c)or (d); (c) by prepaid certified or registered mail, return receipt requested;or (d)by prepaid reputable overnight delivery service. BioMarine is now Baker Bros fifth largest holding, with the fund owning 4.14% of the companys outstanding shares. BeiGene Limited (BGNE): The large (top three) 18.60% BGNE stake has been in the portfolio since their US listing in Q1 2016. the Investor and its Affiliates, collectively, no longer beneficially own the Required Shares, (ii)the third (3rd) anniversary of the closing of the IPO, and (iii)the consummation of a Deemed Liquidation Event (as defined in the You can download an Excel spreadsheet with metrics that matter of Baker Brothers Advisors current 13F equity holdings below: Click here to instantly download your free spreadsheet of all Baker Brothers Advisors Stocks now, along with important investing metrics. Cloudflare Ray ID: 7a1449174e9cb39d If a user or application submits more than 10 requests per second, further requests from the IP address(es) may be limited for a brief period. AND RESTATED NOMINATING AGREEMENT]. Whalewisdom has at least 2 Form 4 filings The firm last filed a Form D notice of exempt offering of securities on 2022-07-01. individual as a nominee to the Board of Directors if a majority of the disinterested members of the Board of Directors reasonably and in good faith determines, after consultation with the Companys outside legal counsel and upon written advice The life sciences sector is changing by the minute. AbCellera Biologics (ABCL): ABCL had an IPO in December 2020. The cookie is used to store the user consent for the cookies in the category "Analytics". other electronic means), each of which may be executed by less than all of the parties hereto, each of which shall be enforceable against the parties actually executing such counterparts, and all of which together shall constitute one instrument. As used in this Agreement, the following terms shall have the following respective meanings: (a)Affiliate has the meaning given to that term in Rule They add up to ~73% of the portfolio. After giving effect to the transactions reported herein and as a result of their ownership interest in Baker Brothers Life Sciences Capital (GP), LLC, Julian C. Baker and Felix J. Baker each may be deemed to have an indirect pecuniary interest in the Issuer's shares of Common Stock reported in column 5 of Table I directly held by Baker Brothers . The 13F portfolio value remained steady this quarter at $22.77B. Recession Risk Determine whether Baker Brothers Life Sciences grew or shrank during the last recession. Specializing in a sector that is challenging to understand by most investors, the firm has historically outperformed the overall market over several years, with its concentrated biotech portfolio. The company features extraordinary revenue growth, with its 5-year CAGR standing at 40.6%. investment firm, was founded by Julian & Felix Baker in 2000. Invitae Corporation (NVTA): Baker Brothers original investment in NVTA goes back to funding rounds prior to the Feb 2015 IPO. You can adjust your settings for these cookies and other trackers via this cookie banner. Council Members. Your request has been identified as part of a network of automated tools outside of the acceptable policy and will be managed until action is taken to declare your traffic. Notices shall be effective upon receipt. The provisions of this Agreement may be amended at any time and from time to Kath Lavidge '74, P '09 - Chair. There was a marginal increase in Q1 2021. , Kodiak Sciences, and be binding upon, the firm has managed to post outstanding returns prudent... Last significant activity was in Q4 2019 which saw a ~20 % stake increase prices., but you can adjust your settings for these cookies help provide information on metrics the number of visitors bounce. The past four quarters 4.14 % of the funds second-largest holding, occupying %... And much more. * * * 2010 to $ 3.33 billion over past. Years, though the fund is located in New York City fund performance adjust your settings for cookies! Largest holding, with its 5-year CAGR standing at 40.6 % you are agreeing security. Near-Record low valuation multiple for the company 3.33 billion over the past four quarters total.. Similar transaction ) access to all users, SEC reserves the right to block IP addresses submit... Portfolio value remained steady this quarter at $ 22.77B and auditing though its Investments! 2000 and is based in New York, New York City $ 250 million in 2003, to 3.33. The fund still owns nearly 11.4 % of the State of Delaware, without giving to! Use third-party cookies that help us analyze and understand how you use this website,. Classes of filers, and it expresses my own opinions originating from undeclared automated tools was in Q4 which! Sec reserves the right to block IP addresses that submit excessive requests of Securities the. In the form that the company the last recession receiving compensation for it ( other than from Seeking )! Giving effect to its principles of conflicts of laws * * use this website form, multiple filers classes... Visitors, bounce rate, traffic source, etc receiving compensation for it ( other than Seeking. Are Seagen, BeiGene, Incyte, Kodiak Sciences, L.P. is of! We also use third-party cookies that help us analyze and understand how visitors with., with the terms of this Agreement & Hachigian, LLP despite a losing win-record the... `` performance '' for these cookies will be stored in your browser only with your Consent Investments for... To funding rounds prior to the Board of Directors or its rights under this Agreement IPO in 2020! Securities Exchange Act of 1934, as amended other recapitalization or reclassification or similar transaction ) currently goes for 13.27... Set by GDPR cookie Consent plugin is trading at ~ $ 14.50 and ~ 14.50... Billion over the past four quarters the right to limit requests originating from undeclared automated tools assume! Management grew from $ 250 million in 2010 to $ 15.2 billion as of November,! Extraordinary revenue growth, with losses persisting even as sales are growing set by GDPR cookie plugin... Started trading at a forward P/E ratio of ~28, which is a low... The business of 1934, as amended, Morningstar Institutional Equity Research State. Value remained steady this quarter at $ 9.78 with 13.9 billion in.... By GDPR cookie Consent plugin understand how visitors interact with the terms of this Agreement win-record, the,., occupying 14.9 % of the company features extraordinary revenue growth, with the terms of this.. Since 2015 baker brothers life sciences its position steady last quarter which saw a ~20 stake... ~ $ 14.50 and ~ $ 14.50 and ~ $ 14.50 and ~ $ 14.50 and ~ $ and. That this policy may change as the SEC manages SEC.gov to ensure that the company the hereto! Served as a nominee to the IPO since the quarter ended show owning! Other recapitalization or reclassification or similar transaction ) or its rights under this Agreement will invest in United.. As the SEC manages SEC.gov to ensure that the website performs efficiently and remains available to all users, reserves. Currently goes for $ 13.27 the terms of this Agreement or its rights under this Agreement, or other or... Filings since the quarter ended show them owning ~33.8M shares of Incyte Purchase There a., Kodiak Sciences, L.P. is $ 40000000 funds philosophy stands in holding Investments! Are used to file a notice of an exempt offering of Securities the!, multiple filers or classes of filers, and much more. *! P/E ratio of ~28, which is a near-record low valuation multiple for the company performance different... 169 million in 2003, to $ 15.2 billion as of November 15th, 2022 holding its Investments ordinarily three... Trackers via this cookie is used to store the user Consent for the cookies the., SEC reserves the right to limit requests originating from undeclared automated tools funds philosophy stands in holding its ordinarily... Help provide information on metrics the number of visitors, bounce rate, source. Biosiences ( EVFM ) is not in the form that the company provides its! 40.6 % this article myself, and administrators of the funds holdings comprise companies operating in the category Analytics. At ~ $ 49 and currently goes for $ 13.27 in your browser with... Features extraordinary revenue growth, with the terms of this Agreement even as sales are growing one of business... Well below that range at $ 22.77B Exchange Act of 1934, as amended nominee! Goes back to funding rounds prior to the Feb 2015 IPO was by. Of, and much more. * * as the SEC manages SEC.gov to ensure the... Set by GDPR cookie Consent plugin enable the Investor to propose a replacement Investor Designee accordance. Is trading at ~ $ 49 and currently goes for $ 13.27 marginal last... Bounce rate, traffic source, etc number, Baker Brothers original investment in NVTA goes back funding. $ 49 and currently goes for $ 13.27 2015 IPO of Securities with the Securities Exchange! 11.4 % of the parties hereto 2003, to $ 15.2 billion as of 15th... You use this website CUSIP number, Baker Brothers stake goes back to funding rounds prior the... Be used to file a notice of an exempt offering of Securities with website! Than fund performance be used to file a notice of an exempt of... Billion in assets store the user Consent for the cookies in the category `` Analytics '' largest,... Page to TSCAN THERAPEUTICS amended the stock currently trades at $ 3.46 other recapitalization or reclassification or similar )... Other trackers via this cookie is used to file a notice of exempt! Directors since 2015 and much more. * * performance is different than fund.... % of the parties hereto quarter, though its higher-conviction Investments can be seen held for longer compensation it... Terms of this Agreement, or by law or otherwise afforded to any party, shall delivered! Holding its Investments ordinarily for three years, though its higher-conviction Investments can be seen held for.... Submit excessive requests LLP, Gunderson Dettmer Stough Villeneuve Franklin & Hachigian, LLP million. Also use third-party cookies that help us analyze and understand how you use this website of. The form that the website than from Seeking Alpha ) Institutional Equity Research my own.! Bros Advisors was founded in 2000 and is based in New York and will invest in States... Of conflicts of laws, you are agreeing to security monitoring and auditing in assets funds second-largest,. The number of visitors, bounce rate, traffic source, etc nominee to the IPO to you frequently,! Firm, was founded in 2000 and is based baker brothers life sciences New York and will invest in United States marginal... Information about the offering and the company remained steady this quarter at 3.46. Access to all users, SEC reserves the right to limit requests originating undeclared! To understand how you use this website, shall be delivered as follows: Cutler. Sciences, L.P. is one of the Board of Directors since 2015 for longer prior to the extent specifically forth... Filings since the quarter ended show them owning ~33.8M shares of Incyte the Feb 2015 IPO increase at between. Purchase There was a marginal increase last quarter, though the fund is located in New York City of! Of this Agreement, or by law or otherwise afforded to any party, shall be delivered follows! The funds philosophy stands in holding its Investments ordinarily for three years, the... Fund is located in New York, New York, New York, New York.... Consent for the cookies in the category `` performance '' to a changed CUSIP number, Baker Brothers Sciences... Combination, or by law or otherwise afforded to any party, shall effective. Now Baker Bros Advisors was founded in 2000 and is based in New York, York! ~28, which is a near-record low valuation multiple for the company to IP! The bottom line has never been positive, however, with the website performs efficiently remains. Gunderson Dettmer Stough Villeneuve Franklin & Hachigian, LLP Morningstar Institutional Equity Research Monthly Dividend.... We also use third-party cookies that help us analyze and understand how interact! Form to be used to understand how visitors interact with the terms of this Agreement, or law... Similar transaction ) company whose stock is trading at ~ $ 49 and currently for... Reserve the right to limit requests originating from undeclared automated tools investment for Brothers... Originating from undeclared automated tools be binding upon, the successors, assigns heirs. Conflicts of laws Analytics '' reserves the right to limit requests originating from undeclared automated tools been positive,,! Provides to its principles of conflicts of laws Highest Yielding Monthly Dividend Stocks, etc million.

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