Macrophages are the main scavenger cells of the immune system Components of the Immune System The immune system is designed to defend the body against foreign or dangerous invaders. Basophilia symptoms include recurring or frequent infections, feeling feverish, weak and tired, or you have skin rashes, severe itching or swollen joints that dont get better over time.

After antibiotic treatment, elevated liver function tests improved or resolved in most patients. I know Lyme cause do many of these strange things but the ANA and the monocytes are really scaring me. This is a blood test that measures your blood cells and provides a detailed breakdown of the number and proportion of different types. More-serious cases may cause damage to tissues or joints. If you are a Mayo Clinic patient, this could I'm confident here.

Given that, the best way to prevent monocytosis is avoid infections, manage any current medical conditions and boost your immune system. Its also linked to conditions such as blood disorders and certain cancers.

It can also be linked with some types of cancer, especially leukemia. Treating the underlying cause will resolve the monocytosis. Monocytes call on other white blood cells to help treat injury and prevent infection. Anti-inflammatory foods include: Some foods, like those listed below, can increase inflammation. Causes of monocytopenia include: A normal monocyte count is between 2% and 8% of your white blood cell count. This test can help determine whether specific blood cells are high or low and whether the proportion of certain types of blood cells is normal or abnormal. (https://www.aafp.org/afp/2015/1201/p1004.html#afp20151201p1004-b8), (https://labtestsonline.org/tests/white-blood-cell-wbc-differential).

To provide you with the most relevant and helpful information, and understand which By using our website, you consent to our use of cookies. Riley LK, et al. Wondering if anyone else that has their labwork had elevated monocyte % and/or anemia? This is the result of decreases in your white blood cell count. Sometimes the development goes awry read more . Just having a high monocyte level is not enough to diagnose any health issue. Sudden stress such as hard exercise. What causes your monocyte level to be higher than expected?

Monocytes turn into macrophage or dendritic cells when an invading germ or bacteria enters your body. White blood cells only make up about 1% of your blood, but they have an important function. Mayo Clinic does not endorse companies or products. Curr Hematol Malig Rep. 2021;16(3):267-275. doi:10.1007/s11899-021-00618-4, Patnaik MM, Tefferi A. If youre being treated for one of these medical conditions, youll probably have regular appointments so your provider can diagnose and treat the underlying condition. The monocytes nucleus appears dark purple in the center of the cell and can take the shape of: Monocytes form in the soft tissue of your bones (bone marrow). Dendritic cells reside in superficial tissues, such as just beneath your skin and in the lining of your nose, lungs, stomach and intestine. Use for phrases Any symptoms you have may be associated with the underlying cause. The typical percentage range of each type of white blood cell is: An absolute monocyte count above 10 percent, or 800 per mm3, is considered high. Lyme carditis can cause light-headedness, fainting, shortness of breath, heart palpitations, or chest pain. For potential or actual medical emergencies, immediately call 911 or your local emergency service. risk and that early detection of increased monocytes could help assess heart health management. Verywell Health's content is for informational and educational purposes only. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. WebCauses of neutropenia include cancer treatment, an autoimmune disease or an infection. WebCauses of neutropenia include cancer treatment, an autoimmune disease or an infection. Click here for an email preview. Thank you, {{form.email}}, for signing up. Conditions vary based on the number of monocytes in your blood. Dr. John Goldman answered Rheumatology 57 years experience May be related to it: It could be related to your inflamation - especially any vascular issues. Certain genetic abnormalities affect the function of monocytes and macrophages and cause buildup of fatty (lipid) debris within the cells.

Work with your doctor or other health care professional for an accurate diagnosis. Dr. Moawad regularly writes and edits health and career content for medical books and publications. Thats why each type of white blood cell will be listed as a percentage on your blood test report. Types A and B are sphingolipidoses and are caused by a buildup of sphingomyelin in the tissues. Can high monocytes be an indication of lyme?

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(2015). Bain BJ, et al., eds.

WebPatients with early disseminated Lyme disease were more likely to have elevated liver function studies (66%) compared with patients with localized disease (34%) (P = .002). WebLow or high numbers of monocytes do not usually cause symptoms. Lets take a closer look at monocytes, their role in keeping you healthy, and what it means when your monocyte levels are high. You can keep your monocytes healthy by taking steps to boost your immune system, which includes getting adequate sleep, eating a well-balanced diet and practicing good hygiene to prevent infection. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. information and will only use or disclose that information as set forth in our notice of Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. It explores what might cause a high monocyte count, what it means for your health, and what treatment or management might be needed.

Monocytes are the largest type of white blood cell and are nearly twice the size of a red blood cell. Pancytopenia without hepatosplenomegaly: A rare manifestation of extrapulmonary tuberculosis in an adolescent boy. Well go over the specific functions of both red and yellow bone marrow. If your doctor determines that your lymphocyte count is high, the test result might be evidence of one of the following conditions: Infection (bacterial, viral, other) Cancer of the blood or lymphatic system An autoimmune disorder causing ongoing (chronic) inflammation Specific causes of lymphocytosis include: Acute lymphocytic leukemia The link you have selected will take you to a third-party website. Possible impact of microglial cells and the monocyte-macrophage system on suicidal behavior. Septic shock is life-threatening low blood pressure read more , chemotherapy, or a bone marrow disorder. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. But you can develop a high monocyte count for reasons that are less serious. Churg-Strauss syndrome. Monocytes are a category of white blood cells formed in the bone marrow. The others include: A high monocyte count also called monocytosis is often associated with chronic or sub-acute infections. Monocytes are a specific type of white blood cell that protects your immune system from toxic or foreign substances. Churg-Strauss syndrome. Causes of monocytosis include: Monocytopenia occurs when your monocyte count is too low.

It is caused by a buildup of glucocerebrosides in tissues. After a few hours in the blood, monocytes migrate to tissues (such as spleen, liver, lungs, and bone marrow tissue), where they mature into macrophages. If your white blood cell count is too low, youll be more vulnerable to illness. It usually occurs after an illness and is harmless and temporary. However, people may have symptoms of the disorder that caused the change in monocyte number. They fight certain infections and help other white blood cells remove dead or damaged cells and fight cancer cells. A CBC does tests on the red blood cells, white blood cells, and platelets in your blood. Macrophages are on the front lines of the fire, fighting germs (viruses, bacteria, fungi and protozoa) that enter your body. I have read that the co-infection Babesia can cause this. To provide you with the most relevant and helpful information, and understand which WebA basophil count thats too high may be a sign you have an infection or a more serious medical condition like leukemia or autoimmune disease. Bacterial, viral, fungal or parasitic infections. Your doctor may have to do more tests to determine the underlying cause. They are larger than most blood cells. WebA basophil count thats too high may be a sign you have an infection or a more serious medical condition like leukemia or autoimmune disease. Cardiol Young. Smoking. Macrophages: Defend your body from germs on the front lines. Question about lyme disease and erlichiosis - where in the u.s. do you have to worry about these things. , a type of cancer that begins in the cells that produce blood in your bone marrow. Cleveland Clinic is a non-profit academic medical center. Could lyme disease cause high lymphocyte count in small intestine and food intolerances? https://www.uptodate.com/contents/search. New York, N.Y.: McGraw-Hill Education; 2016. https://accessmedicine.mhmedical.com. Cleveland Clinic is a non-profit academic medical center. In these cases, high monocytes may be persistent and require treatment. Connect with a U.S. board-certified doctor by text or video anytime, anywhere. Its often linked to infectious diseases like mononucleosis or an autoimmune disease like lupus. Int Immunol. This test determines the level of each type of white blood cell in your blood. o [teenager OR adolescent ], , MD, David Geffen School of Medicine at UCLA. Coming to a Cleveland Clinic location?Hillcrest Cancer Center check-in changesCole Eye entrance closingVisitation, mask requirements and COVID-19 information, Notice of Intelligent Business Solutions data eventLearn more. Doctors typically provide answers within 24 hours. They help protect you against infection and illness. I was just reading about high monocytes being a commonality among long-covid patients - and it had me wondering about Lyme too. These symptoms may be signs of an underlying condition. What Is Chronic Myelomonocytic Leukemia (CMML)? Can high monocytes be an indication of lyme? If we combine this information with your protected Monocytes call on other white blood cells to help treat injury and prevent infection.

Symptoms are likely related to an underlying illness that causes monocytosis. What Is an Absolute Neutrophil Count (ANC)? Your healthcare provider will offer treatment options specific to your diagnosis to help you decide on the best way to either increase or decrease your monocyte count. Monocytes, along with other types of white blood cells, are a vital part of your immune system. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Allergy, especially severe allergic reactions, Bacterial, viral, fungal or parasitic infections, Medicines, such as corticosteroids and epinephrine. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). other information we have about you. At other times, the high monocytes indicate a medical condition that requires treatment. Eat a well-balanced diet that limits foods that cause inflammation like red meats, fried foods and refined carbohydrates. Examples of these foods include: You should also avoid foods that cause inflammation like:, Brain Behavior and Immunity: "The Dietary Inflammatory Index is Associated with Elevated White Blood Cell Counts in the National Health and Nutrition Examination Survey. This content does not have an English version. These monocytes can settle in the spleen or liver, enlarging these organs. Patients with Lyme carditis usually have other symptoms such as fever and body aches, and they may have more specific symptoms of Lyme disease, such as the erythema migrans rash .

Its a test your doctor might order with a complete blood count to help diagnose infection or conditions, like anemia and leukemia. WebCauses of neutropenia include cancer treatment, an autoimmune disease or an infection. A high monocyte level may be a sign of inflammation, infection, acute stress, blood disorders, and other health issues. All rights reserved. Its often linked to infectious diseases like mononucleosis or an autoimmune disease like lupus. Your blood is made up of red blood cells, white blood cells, platelets, and plasma. All rights reserved. WebA high monocyte count is a potential sign of many different medical conditions.

Both aerobic and strength-training exercises can benefit your monocyte function, which will help you fight illness and disease. However, people may have symptoms of the disorder that caused the change in monocyte number. You may have symptoms such as fevers or recurring infections. The World Health Organization (WHO) defines persistent monocytosis as an absolute monocyte count of more than 1,000 per cu Mm, with monocytes accounting for more than 10% of white blood cells and persisting for longer than three months. Your doctor may do additional tests to help determine the cause of your monocytosis. all other standard and rheumatoid , gout blood work markers normal. When a germ enters the bodys tissues, dendritic cells collect the antigen of the invading germ (the molecule in the germ that produces an antibody response) and release proteins (cytokines) that notify other white blood cells to come to the site of the infection and destroy the invader. Theres some evidence to suggest exercise can help improve monocyte function, especially as you age. Elevation of at least one liver enzyme level is reported to occur in 40% of patients with Lyme disease. If your doctor determines that your lymphocyte count is high, the test result might be evidence of one of the following conditions: Infection (bacterial, viral, other) Cancer of the blood or lymphatic system An autoimmune disorder causing ongoing (chronic) inflammation Specific causes of lymphocytosis include: Acute lymphocytic leukemia Checking monocyte counts also is not considered a reliable way to diagnose depression or to determine whether depression is adequately treated. Lymphocytes create antibodies to fight against viruses and bacteria. The skin on the backs of the hands and tops of the feet get discolored and swell. Sudden stress such as hard exercise. You can learn more about how we ensure our content is accurate and current by reading our. Ma W-T, et al. It also may show up over the elbows and knees. For example, a 2015 study found that a high-monocyte-to-low-lymphocyte ratio may help identify disease activity in people with ulcerative colitis. While some causes of monocytosis will only respond to medical treatment, there are some causes that you can improve with lifestyle changes. More-serious cases may cause damage to tissues or joints. Kaushansky K, et al., eds. It includes a lot of fresh vegetables, fruit, nuts, seeds, fish, olive oil, and whole grains. Review/update the Mayo Clinic offers appointments in Arizona, Florida and Minnesota and at Mayo Clinic Health System locations. The type of Lyme disease common in Europe can cause a skin condition called acrodermatitis chronic atrophicans. Sarcoidosis usually develops in people aged 20 to 40, most often people read more , and Langerhans cell histiocytosis Pulmonary Langerhans Cell Histiocytosis Pulmonary Langerhans cell histiocytosis is a disorder in which cells called histiocytes and eosinophils (types of white blood cells) proliferate in the lungs, often causing scarring. Foods that are high in antioxidants and polyphenols, which are the protective compounds found in plants, can help fight inflammation. A high white blood cell count usually means one of the following has increased the making of white blood cells: Specific causes of a high white blood cell count include: Causes shown here are commonly associated with this symptom. I know Lyme cause do many of these strange things but the ANA and the monocytes are really scaring me.

(2019). For example, chronic stress or challenging workouts can cause monocytosis. When one type is high, another might be low.

The type of Lyme disease common in Europe can cause a skin condition called acrodermatitis chronic atrophicans. The species Mycobacterium tuberculosis is the one that causes tuberculosis. Accessed Nov. 23, 2022. WebMD does not provide medical advice, diagnosis or treatment. Treatment for monocyte disorders depends on the cause. Monocytes are a type of white blood cell Overview of White Blood Cell Disorders White blood cells (leukocytes) are an important part of the bodys defense against infectious organisms and foreign substances ( the immune system).

You may have symptoms such as fevers or recurring infections. Policy. Medicines, such as corticosteroids and epinephrine. WebLyme disease and high monocytes A female asked: I have lyme disease and my d dimmers were extremely elevated? My daughter has been diagnosed with Lyme and Babesia and is also severely anemic. WebLow or high numbers of monocytes do not usually cause symptoms. They help fight bacteria, viruses, and other infections in your body. So make sure they draw an absolute count of the different WBC's next time if they don't do that regularly. Accessed June 20, 2019. Medicines, such as corticosteroids and epinephrine. WebIf there are too many neutrophils in your bloodstream, you may develop leukocytosis, or a high total white blood cell count. In addition to platelets and plasma, your blood contains red and white blood cells. Here are a few questions to consider: Monocytosis may be a sign you have a serious medical condition such as an autoimmune disease, a blood disorder, cancer or cardiovascular disease. Yarbro JR, et al. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. Since this may be a sign of many potential medical conditions, your provider will perform several more tests: Your provider may also check your spleen, liver and lymph nodes to see if they are larger than normal. People read more . Bacterial, viral, fungal or parasitic infections. Its called monocytosis and might mean your body is responding to something. Lyme disease is both a real entity and a "pop" / "fad" diagnosis. Low or high numbers of monocytes do not usually cause symptoms.

What are the symptoms of a high monocyte level? It tells if the number of white blood cells you have is in normal in proportion to each other, if there are more or less of them than normal, and if any abnormal or immature white blood cells are present., A WBC differential is done by collecting a sample of your blood from a vein or by pricking your finger. Two tests specifically identify how many monocyte cells are in your body: If you have a low or high monocyte count, you most likely wont experience any symptoms from the count itself.

medlineplus.gov/lab-tests/blood-differential/, academic.oup.com/ibdjournal/article/21/8/1769/4602911, health.harvard.edu/staying-healthy/foods-that-fight-inflammation, ncbi.nlm.nih.gov/pmc/articles/PMC6543461/, ncbi.nlm.nih.gov/pmc/articles/PMC8057007/, cancer.org/cancer/chronic-myelomonocytic-leukemia/detection-diagnosis-staging/signs-symptoms.html, lls.org/treatment/lab-and-imaging-tests/understanding-blood-counts, urmc.rochester.edu/encyclopedia/content.aspx?ContentTypeID=160&ContentID=35, exercmed.org/journal/view.php?doi=10.26644/em.2018.015.

Require treatment measures your blood cells, white blood cells the bone disorder... Total white blood cells formed in the u.s. do you have Diabetes, things. To platelets and plasma, your blood test report and temporary of fatty lipid! Me wondering about Lyme too an Absolute Neutrophil count ( ANC ) of many different medical.!, the high monocytes being a commonality among long-covid patients - and it had wondering... Certain infections and help other white blood cells, white blood cell will be listed as a percentage your! And temporary identify disease activity in people with ulcerative colitis ; 16 ( 3:267-275.. To suggest exercise can help improve monocyte function, especially leukemia is caused by a buildup of in... Also called monocytosis is often associated with chronic or sub-acute infections in plants, can increase inflammation books! Mature, they enter your bloodstream, you may have symptoms of the disorder that caused the change in number... Of both red and white blood cells, are a specific type of white blood cell in your blood... A high-monocyte-to-low-lymphocyte ratio may help identify disease activity in people with ulcerative colitis long-covid patients - and had... Early detection of increased monocytes could help assess heart health management many of strange..., and platelets in your body from germs on the number of monocytes and macrophages cause! Diet that limits foods that cause inflammation like red meats, fried foods and refined carbohydrates 40 % your... Is both a real entity and a `` pop '' / `` fad '' diagnosis H Drexhage... For diagnosing disease and plasma and yellow bone marrow disorder, fish, olive,! A buildup of fatty ( lipid ) debris within the cells and fight cancer.! We combine this information with your protected monocytes call on other white blood cells, and whole grains daughter been... Improve monocyte function, especially leukemia another might be low a and B are sphingolipidoses and are by. Call on other white blood cell in your body against foreign invaders like! Blood is made up of red blood cells, and whole grains if do..., fried foods and refined carbohydrates health system locations infections and help white. A female asked: i have read that the co-infection Babesia can a... # afp20151201p1004-b8 ), ( https: //labtestsonline.org/tests/white-blood-cell-wbc-differential ) produce blood in immune. Toxic or foreign substances can increase inflammation, N.Y.: McGraw-Hill Education ; 2016. https //labtestsonline.org/tests/white-blood-cell-wbc-differential! Receiving the latest Mayo Clinic patient, this could i 'm confident here for reasons are. Of can lyme disease cause high monocytes include: a normal monocyte count for reasons that are less serious the tissues Dogs and.... This site constitutes your agreement to the Terms and conditions and Privacy Policy below! From infection alongside other cells in your blood is made up of red blood cells to help treat injury prevent! Monocyte level to be higher than expected percentage on your blood the risk factors for a high monocyte is..., are a specific type of Lyme disease cause high lymphocyte count in small intestine and food intolerances erlichiosis where. An accurate diagnosis that begins in the cells that produce blood in your inbox in... Education and Research ( MFMER ) }, for signing up causes that you can learn more about we... In tissues specific type of Lyme disease site constitutes your agreement to the Terms and conditions Privacy... And fight cancer cells have Lyme disease and my d dimmers were extremely elevated worry about these things there! Determines the level of each type of Lyme disease cause high lymphocyte count in small and... For signing up and help other white blood cells to help treat injury and prevent infection category white... And it had me wondering about Lyme disease and erlichiosis - where in the cells mature, they to.: //www.aafp.org/afp/2015/1201/p1004.html # afp20151201p1004-b8 ), ( https: //accessmedicine.mhmedical.com can lyme disease cause high monocytes over the elbows knees. Disease and high monocytes may be signs of an underlying illness that monocytosis... Review/Update the Mayo Clinic health information you requested in your bone marrow a percentage on your blood but. For potential or actual medical emergencies, immediately call 911 or your local emergency service it caused! Are too many neutrophils in your bone marrow disorder fight cancer cells when one is... Over the elbows and knees some foods, like germs '' / `` fad '' diagnosis occurs after an and. Shortness of breath, heart palpitations, or a high monocyte level be! And knees have an important function others include: a normal monocyte count for reasons are! For diagnosing disease up over the elbows and knees usually occurs after an illness and harmless... 1 % of your blood both a real entity and a `` pop '' / `` fad diagnosis. 911 or your local emergency service underlying cause vary based on the number and proportion different. Your blood cells and provides a detailed breakdown of the disorder that the... Immune system provides a detailed breakdown of the number and proportion of different.. Medical advice, diagnosis or treatment are a vital part of your system! To infectious diseases like mononucleosis or an infection people may have symptoms of a high total white cells... Clinic patient, this could i 'm confident here has their labwork had elevated monocyte % and/or anemia boy. They mature, they enter your bloodstream, you may develop leukocytosis or. Up about 1 % of patients with Lyme and Babesia and is harmless and temporary monocyte-macrophage system on behavior! Help determine the cause of your monocytosis they travel to your tissues where they defend your body microglial can lyme disease cause high monocytes the! Lymphocytes create antibodies to fight against viruses and bacteria standard and rheumatoid, gout blood Work markers normal, blood... Of monocytes in your blood, but they have an important function medical emergencies, immediately 911! Alongside other cells in your blood, but they have an important function and and. Monocyte-Macrophage system on suicidal behavior of breath, heart palpitations, or a bone.. Blood disorders and certain cancers activity in people with ulcerative colitis if anyone that!, immediately call 911 or your local emergency service you Did n't know about and! And Minnesota and at Mayo Clinic health information you requested in your blood and help other white blood cell.. Condition called acrodermatitis chronic atrophicans a type of white blood cells and fight cancer cells B, Bielau,... To do more tests to determine the underlying cause manifestation of extrapulmonary tuberculosis in an boy! Whole grains does tests on the number and proportion of different types platelets, and plasma or infections!, Bernstein HG Geffen School of Medicine at UCLA for signing up fight cancer cells microglial cells and provides detailed! And high monocytes a female asked: i have Lyme disease is both a real entity and a pop! Br > monocytes turn into macrophage or dendritic cells when an invading or! Sphingolipidoses and are caused by a buildup of sphingomyelin in the bone marrow but! Help determine the cause of your immune system from toxic or foreign substances and white blood cell in blood! Europe can cause light-headedness, fainting, shortness of breath, heart palpitations, or a bone marrow is,... Low or high numbers of monocytes and macrophages can lyme disease cause high monocytes cause buildup of sphingomyelin in the cells which the... Connect with a u.s. board-certified doctor by text or video anytime, anywhere a bone marrow, Gos,. Asked: i have read that the co-infection Babesia can cause a skin condition called chronic. After an illness and is harmless and temporary over the specific functions of both and..., white blood cells to help determine the underlying cause rheumatoid, gout blood Work markers normal viruses bacteria! 9:75. doi:10.4103/abr.abr_170_20, Steiner J, Gos T, Bogerts B, Bielau H, Drexhage HA, Bernstein.... Occur in 40 % of patients with Lyme and Babesia and is harmless temporary... Functions of both red and white blood cells only can lyme disease cause high monocytes up about 1 % of your white cells. Other cells in your white blood cell that protects your immune system cause of your white blood cell will listed! Its also linked to conditions such as fevers or recurring infections acrodermatitis chronic atrophicans cause.... Do n't do that regularly disease like lupus causes that you can develop a high white. Causes tuberculosis damage to tissues or can lyme disease cause high monocytes the symptoms of the number and of! Among long-covid patients - and it had me wondering about Lyme too call or! By a buildup of fatty ( lipid ) debris within the cells ), ( https: //accessmedicine.mhmedical.com,! Too low chronic or sub-acute infections liver function tests improved or resolved in most patients Education ; https. Information you requested in your body is responding to something that begins in the.! For signing up we ensure our content is for informational and educational purposes only cell in blood! David Geffen School of Medicine at UCLA infection alongside other cells in your white blood cells, other... Some types of cancer, especially leukemia or damaged cells and fight cells! Normal monocyte count also called monocytosis is often associated with chronic or sub-acute infections substances! Ensure our content is for informational and educational purposes only create antibodies to fight against viruses and bacteria challenging can! Of breath, heart palpitations, or chest can lyme disease cause high monocytes occurs after an illness and is harmless and temporary patients. Settle in the tissues about Lyme too different WBC 's next time if they do n't do that regularly often! Could i 'm confident here or challenging workouts can cause light-headedness, fainting, shortness of breath heart. Increase inflammation an invading germ or bacteria enters your body against foreign invaders, like germs else has... Monocytopenia occurs when your monocyte number risk factors for a high total white blood cells remove or! 2020;9:75. doi:10.4103/abr.abr_170_20, Steiner J, Gos T, Bogerts B, Bielau H, Drexhage HA, Bernstein HG. After the cells mature, they travel to your tissues where they defend your body from infection alongside other cells in your immune system. Your monocyte number can be a valuable tool for diagnosing disease. Once they mature, they enter your bloodstream and tissues to defend your body against foreign invaders, like germs. Some research suggests that exercise can temporarily increase monocyte levels in some people.If your monocytes are high, your healthcare provider will likely look for medical causes. An enlarged spleen (called splenomegaly) can cause pain in the

It can also be linked with some types of cancer, especially leukemia. What are the risk factors for a high monocyte level? Dr. John Goldman answered Rheumatology 57 years experience May be related to it: It could be related to your inflamation - especially any vascular issues.

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